At her design studio in Soho, Janet van Dyne looks through matching uniform ideas she had for herself and her ex-husband, Hank Pym. "Hank Pym" shows up and gives her an "Anniversary Present", an improved growth formula that should allow her to easily switch from Wasp to Giant Woman. The next day, the Mighty Avengers face thousands of Venom Virus hosts on the streets of New York City. The symbiotes swarm the Sentry. While Ares prepares to chop them in half, Janet changes from Wasp to Giant Woman. However, the symbiotes bite her and turn her into one of them. Realizing the symbiote is infecting real people, Iron Man instructs his teammates to try to avoid fighting with these symbiotes, instead making sure they do not hurt each other. The Mighty Avengers learn that all of the New Avengers except Luke Cage have been infected, too. Iron Man collects the original container of the virus and an infected dog and brings them to the Baxter Building to find the cure.