2099: World of Tomorrow brings together many cancelled titles and therefore contains many concurrent plot lines. The overarching storyline takes place in the Savage Land, Latveria, and the Alchemax Ares Colony on Mars. Prior to the start of the title, the polar ice caps have melted, due to a small planetoid entering the atmosphere, which is revealed to be the Phalanx collective. This floods the world, killing 90% of the world's population and driving the last remnants of humanity to higher ground or on large armadas of skifs drifting in the waters.