After destroying Brainiac's shell, Psimon turns his attention towards Lex Luthor. He plans on taking over the united villains after killing Luthor. What Psimon doesn't realize however is that Brainiac's consciousness is downloaded into the circuitry of his ship. He forges a new body for himself and blasts the top off of Psimon's crown with a beam of energy. On Earth-One at the dawn of mankind, Anthro continues to see wild streaks of red lightning flashing across the sky. He ponders whether he should tell the rest of the tribe, but fears that they may find him crazy. On Earth-Four, Chemo stands next to the ruins of the Statue of Liberty. All about him, the waters surrounding Manhattan island are bubbling with deadly poisonous fumes. Negative Woman flies about him, ensnaring the gigantic villain with bands of shadow energy. The bands constrict until they eventually succeed in destroying Chemo's artificial shell. In Manhattan, Black Adam fights up against Robotman and Dove. Kole of the New Teen Titans flies up behind him and turns his body into solid crystal. Robotman is prepared to shatter him, but Dove holds him back. Meanwhile, Cyborg and Celsius tackle Quakemaster. Meanwhile, Aqualad races back to Atlantis carrying Aquagirl's body. He hands her over to the city's medical specialists, but there is nothing they can do. Aquagirl is dead. In the frozen wastelands of Earth-S, Doctor Sivana, Doctor Cyber, Per Degaton, Houngan, Phobia, Despero, Deathbolt, Hector Hammond and Professor T.O. Morrow keep watch over the captured members of the Marvel Family. While Sivana is in the midst of gloating, the Martian Manhunter burrows through the ice and attacks them. He blasts at Deathbolt with his Martian vision. The Atom and Platinum of the Metal Men arrive to give him back-up. Phobia tries to use her powers on Platinum, but they fail, enabling the Atom enough time to loose the gag around Billy Batson's mouth. Billy shouts the magic word, "Shazam" and transforms into Captain Marvel. On Earth-X , Batman and the original Atom fight up against Calendar Man while the Outsiders and Infinity, Inc. take on the Dummy. Hawkwoman and Tin fight Lightning Lord, and Firestorm and Vixen fight up against Captain Cold and Icicle. Green Arrow of Earth-Two assists Changeling and Mento in combating the Shaggy Man. Green Arrow defeats the Shaggy Man with an explosive-tipped arrow. Suddenly, the Spectre makes his presence known across the five partially merged Earths. He warns all of the heroes that the Anti-Monitor is still alive and that he has retreated into the past to change the course of history at the dawn of time itself. The heroes migrate to Earth-One to coordinate their efforts. They form their teams and develop a strategy using the time-traveling capabilities of the Time Masters, the Legion of Super-Heroes and the Lord of Time. Flash (Jay Garrick) and Kid Flash are outfitted with converter technology to help bridge the gap. With the aid of Magno Lad, Cosmic Boy and Gold, the team creates a large magnetic conductor, which shunts the assemblage backwards in time. Meanwhile, Lex Luthor and his allies travel backwards in time ten billion years to the planet Oa. They arrive on the fateful day when the scientist Krona is destined to witness the hand of creation and inadvertently create the Multiverse. They burst into his laboratory, but Krona is ready for them. He kills Icicle, Mirror Master and Maaldor. At the dawn of time, the heroes face the Anti-Monitor. They channel all of their energy into him, but this only serves to make the Anti-Monitor more powerful. He requires their energy so that when Krona opens the doorway between the positive matter universe and the antimatter universe, the Anti-Monitor will then be able to obliterate the positive matter universe entirely. The Spectre appears before the Anti-Monitor, channeling all of the mystical energy of Earth's most powerful sorcerers. He attacks the Anti-Monitor directly and their fight unleashes an explosion of energy, which appears to consume all reality.