Dr. Octopus organizes the Sinister Six, composed of other Spider-Man Villains. They capture Betty Brant and Aunt May and force Spider-Man to rescue them.
Note: The story is reprinted in the wrong place in continuity (several villains aren't introduced until future issues). In this reprint, alterations are made to the dialogue and artwork. Aunt May bemoans missing The Dukes of Hazzard, in the original it was The Beverly Hillbillies.