The Red Ghost is back, and he's brought his super-apes with him! Red, Sue, Ben, and Johnny are face-to-face with one of their greatest foes from the past! After the final foe was apprehended, Reed discovered the source of his paranoia, a device hidden in his lab had been subliminally suggesting his family's demise. Moments after this discovery, the DNA samples that the Mad Thinker had gathered began to dissolve. At that very moment, while on a tour of the prison, Andrew Lewis's hideous wife staged a jailbreak at the newly-completed Vault, seemingly masterminded by none other than the Mad Thinker.